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Biogen Inc. Press Release: “LEQEMBI®” (lecanemab) for the Treatment of Early Alzheimer's Disease Included in China's Commercial
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# “LEQEMBI®” (lecanemab) for the Treatment of Early Alzheimer's Disease Included in China's Commercial Insurance Innovative Drug List **Date:** 2025-12-08 18:30:00 **Company:** Biogen Inc. **Ticker:** BIIB **Source URL:** https://www.globenewswire.com/news-release/2025/12/08/3202014/0/en/LEQEMBI-lecanemab-for-the-Treatment-of-Early-Alzheimer-s-Disease-Included-in-China-s-Commercial-Insurance-Innovative-Drug-List.html --- [Accessibility: Skip TopNav](https://www.globenewswire.com/news-release/2025/12/08/3202014/0/en/LEQEMBI-lecanemab-for-the-Treatment-of-Early-Alzheimer-s-Disease-Included-in-China-s-Commercial-Insurance-Innovative-Drug-List.html#maincontainer) [](https://www.globenewswire.com/) - [Newsroom](https://www.globenewswire.com/newsroom) - [Services](https://www.globenewswire.com/services) - [Contact Us](https://insight.notified.com/globenewswire-contact-us?utm_medium=Website&utm_source...
# “LEQEMBI®” (lecanemab) for the Treatment of Early Alzheimer's Disease Included in China's Commercial Insurance Innovative Drug List **Date:** 2025-12-08 18:30:00 **Company:** Biogen Inc. **Ticker:** BIIB **Source URL:** https://www.globenewswire.com/news-release/2025/12/08/3202014/0/en/LEQEMBI-lecanemab-for-the-Treatment-of-Early-Alzheimer-s-Disease-Included-in-China-s-Commercial-Insurance-Innovative-Drug-List.html --- [Accessibility: Skip TopNav](https://www.globenewswire.com/news-release/2025/12/08/3202014/0/en/LEQEMBI-lecanemab-for-the-Treatment-of-Early-Alzheimer-s-Disease-Included-in-China-s-Commercial-Insurance-Innovative-Drug-List.html#maincontainer) [](https://www.globenewswire.com/) - [Newsroom](https://www.globenewswire.com/newsroom) - [Services](https://www.globenewswire.com/services) - [Contact Us](https://insight.notified.com/globenewswire-contact-us?utm_medium=Website&utm_source=Contact%20Us&utm_campaign=Contact%20Us%20ENG) - English [Sign In](https://www.globenewswire.com/home/signin) [Register](https://portal.notified.com/en/registration) # [](https://www.biogen.com/) # “LEQEMBI®” (lecanemab) for the Treatment of Early Alzheimer’s Disease Included in China’s Commercial Insurance Innovative Drug List December 08, 2025 18:30 ET\| Source: [Biogen Inc.](https://www.globenewswire.com/en/search/organization/Biogen%2520Inc%C2%A7)FollowBiogen Inc. * * * Share - * * * TOKYO and CAMBRIDGE, Mass., Dec. 08, 2025 (GLOBE NEWSWIRE) -- Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”) and Biogen Inc. (Nasdaq: BIIB, Corporate headquarters: Cambridge, Massachusetts, CEO: Christopher A. Viehbacher, “Biogen”) announced today that anti-Aβ protofibril\* antibody “LEQEMBI®” (brand name in China: “乐意保®”, generic name: lecanemab), has been included in the “Commercial Insurance Innovative Drug List” (Chinese: 商业健康保险创新药品目录), recently introduced by the National Healthcare Security Administration (NHSA) of China. The inclusion of LEQEMBI in this list marks a meaningful step toward expanding access to early Alzheimer’s Disease (AD) treatment in China. The Commercial Insurance Innovative Drug List is based on new policies of the Chinese government to support the development and access of innovative medicines. The list aims to help narrow the coverage gap between the basic reimbursement system under the National Reimbursement Drug List (NRDL) and innovative medicines that address areas of significant unmet need. Based on the Commercial Insurance Innovative Drug List, Commercial insurance companies will discuss and reach the agreement with pharmaceutical companies regarding coverage details, and develop insurance products focusing on the listed medicines. The Commercial Insurance Innovative Drug List is scheduled to take effect on January 1, 2026. Eisai estimates that there were 17 million patients with MCI or mild dementia due to AD in China in 2024, which is expected to increase with the aging of the population. Eisai launched LEQEMBI in China in June 2024 and has delivered the product in the private market. Eisai serves as the lead of LEQEMBI development and regulatory submissions globally with Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision-making authority. Eisai will distribute the product in China and will conduct information provision activities through specialized Medical Representatives. \*Protofibrils are believed to contribute to the brain injury that occurs with AD and are considered to be the most toxic form of Aβ, having a primary role in the cognitive decline associated with this progressive, debilitating condition.1 Protofibrils cause injury to neurons in the brain, which in turn, can negatively impact cognitive function via multiple mechanisms, not only increasing the development of insoluble Aβ plaques but also increasing direct damage to brain cell membranes and the connections that transmit signals between nerve cells or nerve cells and other cells. It is believed the reduction of protofibrils may prevent the progression of AD by reducing damage to neurons in the brain and cognitive dysfunction.2 | | | | --- | --- | | **MEDIA CONTACTS** | | | **Eisai Co., Ltd.**<br>Public Relations Department<br>TEL: +81 (0)3-3817-5120<br>**Eisai Europe, Ltd.**<br>EMEA Communications Department<br>+44 (0) 797 487 9419<br>[Emea-comms@eisai.net](mailto:Emea-comms@eisai.net "Emea-comms@eisai.net")<br>**Eisai Inc. (U.S.)**<br>Libby Holman<br>+1-201-753-1945<br>[Libby\_Holman@Eisai.com](mailto:Libby_Holman@Eisai.com "Libby_Holman@Eisai.com") | **Biogen Inc.**<br>Madeleine Shin <br>+1-781-464-3260<br>[public.affairs@biogen.com](mailto:public.affairs@biogen.com "public.affairs@biogen.com") | | **INVESTOR CONTACTS** | | | **Eisai Co., Ltd.**<br>Investor Relations Department<br>TEL: +81 (0) 3-3817-5122 | **Biogen Inc.**<br>Tim Power<br>\+ 1-781-464-2442<br>[IR@biogen.com](mailto:IR@biogen.com "IR@biogen.com") | **Notes to Editors** 1. **About LEQEMBI (generic name: lecanemab, Chinese brand name:** **乐意保** **)** Lecanemab is the result of a strategic research alliance between Eisai and BioArctic. It is a humanized immunoglobulin gamma (IgG1) monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta (Aβ). Lecanemab has been approved in 51 countries and is under regulatory review in 9 countries. Following the initial phase with treatment every two weeks for 18 months, intravenous (IV) maintenance dosing with treatment every four weeks was approved in the U.S., China, the UK, and others, and applications have been filed in 4 countries and regions. The U.S. FDA approved Eisai’s Biologics License Application (BLA) for subcutaneous maintenance dosing with LEQEMBI IQLIK in August 2025. A rolling Supplemental Biologics License Application (sBLA) for initiation treatment was initiated under Fast Track status in September 2025, and completed in November 2025. In November 2025, an application for a subcutaneous injectable formulation in Japan was submitted. Since July 2020 the Phase 3 clinical study (AHEAD 3-45) for individuals with preclinical AD, meaning they are clinically normal and have intermediate or elevated levels of amyloid in their brains, is ongoing. AHEAD 3-45 is conducted as a public-private partnership between the Alzheimer's Clinical Trial Consortium that provides the infrastructure for academic clinical trials in AD and related dementias in the U.S, funded by the National Institute on Aging, part of the National Institutes of Health, Eisai and Biogen. Since January 2022, the Tau NexGen clinical study for Dominantly Inherited AD (DIAD), that is conducted by Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU), led by Washington University School of Medicine in St. Louis, is ongoing and includes lecanemab as the backbone anti-amyloid therapy. 2. **About the Collaboration between Eisai and Biogen for AD** Eisai and Biogen have been collaborating on the joint development and commercialization of AD treatments since 2014. Eisai serves as the lead of lecanemab development and regulatory submissions globally with both companies co-commercializing and co-promoting the product and Eisai having final decision-making authority. 3. **About the Collaboration between Eisai and BioArctic for AD** Since 2005, Eisai and BioArctic have had a long-term collaboration regarding the development and commercialization of AD treatments. Eisai obtained the global rights to study, develop, manufacture and market lecanemab for the treatment of AD pursuant to an agreement with BioArctic in December 2007. The development and commercialization agreement on the antibody lecanemab back-up was signed in May 2015. 4. **About Eisai Co., Ltd.** Eisai's Corporate Concept is "to give first thought to patients and people in the daily living domain, and to increase the benefits that health care provides." 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Except as required by law, we do not undertake any obligation to publicly update any forward-looking statements whether as a result of any new information, future events, changed circumstances or otherwise. **Digital Media Disclosure** From time to time, we have used, or expect in the future to use, our investor relations website (investors.biogen.com), the Biogen LinkedIn account (linkedin.com/company/biogen-) and the Biogen X account ( [https://x.com/biogen](https://www.globenewswire.com/Tracker?data=yaXjcB1olHoWA7FUSt9nOdLia-Y3cM6NQy9VaFeZ1I6x3n8IRc-IDxQPAcz9JZasOWdUTyJ1ijeDgw9n0EVZjgJ1oWUTFefvd9hQXc-_V-0= "")) as a means of disclosing information to the public in a broad, non-exclusionary manner, including for purposes of the SEC’s Regulation Fair Disclosure (Reg FD). Accordingly, investors should monitor our investor relations website and these social media channels in addition to our press releases, SEC filings, public conference calls and websites, as the information posted on them could be material to investors. **References** 1. Amin L, Harris DA. Aβ receptors specifically recognize molecular features displayed by fibril ends and neurotoxic oligomers. _Nat Commun_. 2021;12:3451. doi:10.1038/s41467-021-23507-z 2. Ono K, Tsuji M. Protofibrils of Amyloid-β are Important Targets of a Disease-Modifying Approach for Alzheimer's Disease. _Int J Mol Sci._ 2020;21(3):952. doi: 10.3390/ijms21030952. PMID: 32023927; PMCID: PMC7037706.  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